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A prospective study of atilizumab, bevacizumab and Huaier granules in the treatment of unresectable liver cancer

A prospective study of atilizumab, bevacizumab and Huaier granules in the treatment of unresectable liver cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045870
Enrollment
Unknown
Registered
2021-04-25
Start date
2021-07-01
Completion date
Unknown
Last updated
2021-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cancer

Interventions

Experimental group:Atelizumab, bevacizumab combined with Huaier granules
Control group:Atelizumab, bevacizumab

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years, regardless of gender; 2. The diagnosis of HCC is confirmed by imaging examination, serum alpha-fetoprotein (AFP) examination or pathology, and cannot accept surgical resection; 3. According to the modified solid tumor efficacy evaluation criteria (mRECIST), there is at least one target lesion that can be evaluated; 4. Karnofsky (KPS) score >= 60 points; 5. Child-Pugh score of liver function = 12 weeks; 7. Have not received chemotherapy, immunotherapy, targeted therapy and other systemic treatment methods before enrollment or during the study period; 8. Patients and their families are willing to cooperate with follow-up.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating women; 2. Cannot tolerate Chinese medicine; 3. Patients who refuse to participate or withdraw from the study halfway through.

Design outcomes

Primary

MeasureTime frame
Blood routine;Liver function;Kidney function;Alpha-fetoprotein;Abdominal CT;

Countries

China

Contacts

Public ContactTian Weijun

Tianjin Medical University General Hospital

jonathontian@163.com+86 13920451390

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026