Postoperative nause and vomiting
Conditions
Interventions
The control group:Induction of anesthesia with sufentanil
The experimental group:Induction of anesthesia with butorphanol tartrate
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged over 65 years; 2. ASA I-III; 3. The operation time is 2h-4h; 4. Patients who intend to have endotracheal intubation under laparoscopic gastrointestinal surgery under intravenous anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to this product and its ingredients; 2. Patients who are dependent on opioid analgesics; 3. There are obvious neurological and mental diseases; 4. Are taking sedatives, analgesics and antidepressants; 5. Renal insufficiency (serum creatinine > 177µmol/l) or active liver disease; 6. Severe respiratory complications before surgery; 7. Severe OSAHS and obesity (BMI>= 30); 8. Severe visual and hearing impairment, which affects communication; 9. Have a history of gastrointestinal ulcers and blood system diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incident of agitation in the PACU after extubation;Post-extubation BCS score;Intraoperative dosage of propofol and remifentanil;Postoperative exhaust time; | — |
Countries
China
Contacts
Public ContactSun Defeng
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed