To exploring the brain and spinal cord microenvironment changes of the spinocerebellar ataxia by multi-parameter MRI

Using Multi-Parameter MRI to Study the Functional, Morphological and Metabolic Alterations of the Brain and Spine Microstucre in Spinal Cerebellar Ataxia Patients

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100045857

Enrollment

Unknown

Registered

2021-04-25

Start date

2018-05-01

Completion date

Unknown

Last updated

2021-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Cerebellar Ataxia

Interventions

Case series:Nil

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. All the patients diagnosis has been proved by the molecular genetic testing; 2. Aged > 18 years; 3. Right handedness.

Exclusion criteria

Exclusion criteria: 1. Combined with other mental disorders, personality disorders, or psychotropic drug dependence; 2. Difficult to cooperate during MRI examination, and the image quality is too poor for image analysis; 3. Combined with a history of other brains organic and metabolic diseases; 4. Pregnant and lactating women; 5. Other MRI contraindications.

Design outcomes

Primary

Measure	Time frame
indices of diffusion imaging ;indices of blood oxygenation level dependent;indices of high-resolution three-dimensional T1WI;indices of perfusion weighted imaging;indices of MRS;indices of SWI;indices of neuromelanin imaging;	—

Countries

China

Contacts

Public ContactChu Jianping

The First Affiliated Hospital of Sun Yat-Sen University

truechu@hotmail.com+86 18620195866

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026