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The mechanisms of LncRNA-SNHG16-mediated mitochondrial transfer regulating the interactive dialogue between mesenchymal stem cells and endothelial cells to promote endothelial repair in ARDS

The mechanisms of LncRNA-SNHG16-mediated mitochondrial transfer regulating the interactive dialogue between mesenchymal stem cells and endothelial cells to promote endothelial repair in ARDS

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100045856
Enrollment
Unknown
Registered
2021-04-25
Start date
2021-05-14
Completion date
Unknown
Last updated
2021-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome (ARDS)

Interventions

case series:Null

Sponsors

Zhongda Hospital, School of Medicine, Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed of ARDS; 2. Patients admitted to ICU for more than 24 hours; 3. Aged 18 to 80 years; 4. Patients with informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with acute and chronic hepatitis or cirrhosis or liver transplantation. 2. Patients with acute myocardial infarction; 3. Pregnant patients or tumor patients; 4. Patients with immune deficiency disease; 5. Patients had extensive use of glucocorticoids (equivalent dose >Prednisone 10mg/d) or immunosuppressant 6 months before admission.

Design outcomes

Primary

MeasureTime frame
28 Day mortality;ARDS Severity;—

Countries

China

Contacts

Public ContactMeng Shanshan

Zhongda Hospital, School of Medicine, Southeast University

mengshanshan0101@163.com+86 13705171687

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026