Effect of glycopyrrolate on imaging quality of sublingual microcirculation in children with congenital heart disease during operation

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100045841

Enrollment

Unknown

Registered

2021-04-25

Start date

2021-06-01

Completion date

Unknown

Last updated

2021-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Children with congenital heart disease

Interventions

control group:Intravenous injection of 2ml normal saline

glycopyrrolate group:Intravenous injection of 2ml glycopyrrolate (0.005mg/kg)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. ASA I-II; 2. Aged 6-12 years; 3. Simple atrial septal defect or ventricular septal defect.

Exclusion criteria

Exclusion criteria: 1. Preoperative combined with severe pulmonary hypertension; 2. With Down syndrome; 3. Known allergy to glycopyrrolate; 4. Oral mucosa injury or disease.

Design outcomes

Primary

Measure	Time frame
Mucosal secretion of tongue frenulum;Satisfaction of sublingual microcirculation imaging;Heart rate and blood pressure of children within 20min minutes after anesthesia induction;	—

Countries

China

Contacts

Public ContactLin Hongqi

Fuwai Huazhong Cardiovascular Hospital

457741630@qq.com+86 15617770159

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026