polycystic ovary syndrome
Conditions
Interventions
Group A:2.5mg letrozole
Group B:5.0mg letrozole
Sponsors
Union Hospital,Tongji Medical College,Huazhong University of Science and Technology
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. PCOS patients who meet the 2003 Rotterdam diagnostic criteria: (1) The patient has sparse ovulation or even anovulation; (2) The patient's clinical symptoms or biochemical manifestations show hyperandrogenemia; (3) Abdominal color Doppler ultrasound shows polycystic changes in the ovaries (vaginal color Doppler ultrasound shows that the number of follicles containing 2-9 mm in one or even both sides of the ovaries is greater than 12); The diagnosis can be made if two of the above three criteria are met. 2. Younger than 40 years old, no abnormal sexual life, infertility course not less than 1 year; 3. Hysterosalpingography shows that the uterus is normal, and at least one fallopian tube is unobstructed; 4. The results of spouse's sperm analysis are no abnormal or mildly low and asthenospermia; 5. The function of various organs is normal, without any endocrine diseases such as hypopituitarism, hyperthyroidism, etc.
Exclusion criteria
Exclusion criteria: 1. Those who are known to be allergic to related drugs; 2. Combined with mental or neurological diseases, unable to actively cooperate with the test; 3. Previously suffering from abnormal diseases of the uterus or uterine cavity; 4. Past exposure to teratogenic toxins, radiation, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovulation rate;Total pregnancy rate;Clinical pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Singleton pregnancy rate;Multiple pregnancy rate;Ectopic pregnancy rate;Early pregnancy loss rate;Number of patients;Number of cycles; | — |
Countries
China
Contacts
Public ContactLiu Yi
Union Hospital,Tongji Medical College,Huazhong University of Science and Technology
Outcome results
None listed