Early predictive value of urine [TIMP-2]·[IGFBP-7] for acute kidney injury after major abdominal surgery in elderly patients with hypertension

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100045828

Enrollment

Unknown

Registered

2021-04-25

Start date

2021-05-01

Completion date

Unknown

Last updated

2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Interventions

Hypertensiongroup :No

Normotensiongroup:No

Eligibility

Sex/Gender

All

Age

60 Years to 89 Years

Inclusion criteria

Inclusion criteria: 1. Aged >= 60 years; 2. ASA I~III grade; 3. Patients undergoing major abdominal surgery under elective general anesthesia; 4. Estimated operation time >= 2h; 5. With or without a history of hypertension.

Exclusion criteria

Exclusion criteria: 1. Recent history of heart failure and myocardial infarction; 2. Severe heart disease (severe valve disease, heart failure, etc.); 3. Ejection fraction = B grade); 6. Intraoperative need for controlled blood pressure reduction; 7. History of kidney disease surgery; 8. Those who have used contrast media before surgery; 9. Acute and chronic renal insufficiency; 10. Has participated in other pilot projects.

Design outcomes

Primary

Measure	Time frame
Tissue inhibitor of metalloproteinase-2;Insulin-like growth factor binding protein-7;	—

Countries

China

Contacts

Public ContactLiu Jindong

Affiliated Hospital of Xuzhou Medical University

Liujindong1818@163.com+86 13951355136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026