Effect of high-definition transcranial direct current stimulation on conditioned pain modulation in healthy adults: a crossover randomized controlled trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100045811

Enrollment

Unknown

Registered

2021-04-25

Start date

2021-05-01

Completion date

Unknown

Last updated

2021-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group 1 vs. Group 2:first cycle: active stimulation-false stimulation

second cycle: false stimulation-true active stimulation.

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Right-handed (Edinburgh); 2. Aged 18 to 40 years; 3. No history of habitual smoking or drinking; 4. Not during the menstrual cycle or during pregnancy, exclude the influence of periodic fluctuations of steroid hormones on the pain threshold and cortical excitability parameters during the menstrual cycle; 5. The score of Beck Depression Inventory (BDI-II) is lower than 14 points.

Exclusion criteria

Exclusion criteria: 1. Unstable psychology and mental illness; 2. Drug abuse or routine drug use in the past 3 months; 3. Acute or chronic pain in the past 3 months; 4. There is currently a disease in the hand; 5. Based on documented tDCS contraindications (such as implantation of medical equipment or history of epilepsy).

Design outcomes

Primary

Measure	Time frame
conditioned pain modulation;	—

Countries

China

Contacts

Public ContactWang Yuling /Wan Ruihan

The Sixth Affiliated Hospital of Sun Yat-Sen University

wangyul@mail.sysu.edu.cn+86 13054446687

Outcome results