chemotherapy induced peripheral neuropathy
Conditions
Sponsors
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with tumors diagnosed by pathological cytology or histology; 2.There were numbness, hypoesthesia, pain and paresthesia in extremities after chemotherapy with platinum or taxanes. Some patients have muscle spasm, muscle weakness, myalgia, and even paralysis; 3.Peripheral neuropathy of grade 1 or above according to NCI adverse reaction evaluation criteria within 7 days to 2 years after stopping chemotherapy; 4.The main TCM syndrome is qi deficiency and blood stasis; 5.The Eastern Oncology Cooperative Group (EOCG) score is 0-3; 6.The expected survival time is more than 3 months.
Exclusion criteria
Exclusion criteria: 1.Patients receiving other medications that may cause neurotoxicity; 2.Receive any drugs that are suspected to be effective, such as tricyclic antidepressants or anticonvulsants; 3.Patients with severe heart, liver, kidney, immune and hematopoietic system diseases; 4.Pregnant women and lactating women; 5.Patients are fear of acupuncture, allergy to stainless steel needle and other reasons can not accept acupuncture treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Classification of NCI-CTCAE peripheral neuropathy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Score of EORTC QLQ-CIPN20 Scale;Digital pain grading score;syndrome of qi deficiency and blood stasis; | — |
Countries
China
Contacts
Public ContactXu Weiru
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Outcome results
None listed