Skip to content

Brain function and brain network remodeling in patients with movement disorders after deep brain stimulation

Brain function and brain network remodeling in patients with movement disorders after deep brain stimulation

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100045755
Enrollment
Unknown
Registered
2021-04-24
Start date
2021-04-20
Completion date
Unknown
Last updated
2021-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Movement Disorders

Interventions

Control group:None
movement disorders group :None

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18 to 70 years, male or female; 2.Diagnosed as movement disorders consistent with diagnostic criteria from the International Parkinson and Movement Disorder Society, including Parkinson's disease, dystonia, Huntington's disease, chorea-acanthocytosis and so on. 3.0-24 days after DBS surgery, and no obvious side effects of non-motor symptoms caused by stimulation 4.The patient and/or his/her legal guardian agreed to participate in the clinical trial and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1.With a history of head trauma or epilepsy; 2.Substance related addiction disorders; Or other mental illness; 3.Complicated with serious functional impairment of heart, liver, lung, kidney and other important organs; 4.Low intelligence (MMSE score: illiteracy <=17 points, primary school graduate <= 20 points, middle school graduate and above <=24 points); 5.Have received exploratory therapy as a subject in other clinical studies in the past 1 year; 6.Have received surgical treatment other than deep brain stimulation, such as stereotactic damage, cell transplantation, gamma knife, etc..

Design outcomes

Primary

MeasureTime frame
Electroencephalogram (EEG) signals during motor function execution;

Secondary

MeasureTime frame
Local field potential (LFP) signals during motor function execution;Electroencephalogram (EEG) and Local field potential (LFP) signals during sensory function execution;Electroencephalogram (EEG) and Local field potential (LFP) signals during cognitive function execution;Electroencephalogram (EEG) and Local field potential (LFP) signals during resting state;

Countries

China

Contacts

Public ContactCao Li

Shanghai Sixth People's Hospital

wujy@rjlab.cn+86 13472610202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026