Movement Disorders
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 70 years, male or female; 2.Diagnosed as movement disorders consistent with diagnostic criteria from the International Parkinson and Movement Disorder Society, including Parkinson's disease, dystonia, Huntington's disease, chorea-acanthocytosis and so on. 3.0-24 days after DBS surgery, and no obvious side effects of non-motor symptoms caused by stimulation 4.The patient and/or his/her legal guardian agreed to participate in the clinical trial and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1.With a history of head trauma or epilepsy; 2.Substance related addiction disorders; Or other mental illness; 3.Complicated with serious functional impairment of heart, liver, lung, kidney and other important organs; 4.Low intelligence (MMSE score: illiteracy <=17 points, primary school graduate <= 20 points, middle school graduate and above <=24 points); 5.Have received exploratory therapy as a subject in other clinical studies in the past 1 year; 6.Have received surgical treatment other than deep brain stimulation, such as stereotactic damage, cell transplantation, gamma knife, etc..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electroencephalogram (EEG) signals during motor function execution; | — |
Secondary
| Measure | Time frame |
|---|---|
| Local field potential (LFP) signals during motor function execution;Electroencephalogram (EEG) and Local field potential (LFP) signals during sensory function execution;Electroencephalogram (EEG) and Local field potential (LFP) signals during cognitive function execution;Electroencephalogram (EEG) and Local field potential (LFP) signals during resting state; | — |
Countries
China
Contacts
Shanghai Sixth People's Hospital