Alzheimer's disease
Conditions
Interventions
Gold Standard:According to the diagnostic criteria of neurologists, the diagnosis was made by the scores of comprehensive scale, CSF examination and MRI.
Index test:PET/CT, 
scale:MMSE, 
MoCA-B, 
AVLT, 
Boston 
naming,HAMA, 
HAMD, 
STT.
Sponsors
The First Affiliated Hospital of Zhenghzou University
Eligibility
Sex/Gender
All
Age
50 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Patients with subjective cognitive impairment, mild cognitive impairment and ad disease; 2.The age is between 50-90 years old; 3.The mother tongue is Chinese, and the length of education is more than 5 years; 4.Qualified persons accompanied by the informants participated in the study; 5.Patients could cooperate with the examination; 6.Agree to PET study and follow-up for at least three years; 7.Voluntary participation and informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with vascular diseases, mental diseases, brain space occupying lesions, history of brain trauma, long-term alcoholism and epilepsy that can cause dementia or cognitive impairment. 2.Pregnancy, lactation, or childbearing age.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Standard uptake value ratio;Aß1-40;p-tau; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rating scale; | — |
Countries
China
Contacts
Public ContactHan Xingmin
The First Affiliated Hospital of Zhenghzou University
Outcome results
None listed