heart failure with preserved ejection fraction
Conditions
Interventions
Gold Standard:Brain natriuretic peptide, magnetic resonance, nuclide.
Auto 
VQ 
and 
STI 
technology
Sponsors
People's Hospital of Shapingba District, Chongqing
Eligibility
Sex/Gender
All
Age
30 Years to 100 Years
Inclusion criteria
Inclusion criteria: HFPEF group: According to the HFpEF diagnostic criteria of the 2018 Chinese Heart Failure Diagnosis and Treatment Guidelines, 100-120 patients with HFpEF from May 2022 to August 2023 were collected: 1.There are signs or symptoms of congestive heart failure: pulmonary rales, pulmonary edema, ankle swelling, hepatomegaly, difficulty breathing during exercise or resting, fatigue, etc.; 2.Left ventricular systolic function: LVEF>50%; 3.Increased natriuretic peptide: B-type natriuretic peptide (BNP)>35ng/L and/or N-terminal B-type natriuretic peptide (NT-proBNP)>125ng/L. 4.Related structural heart disease (LV hypertrophy or LA enlargement), or abnormal diastolic function. Abnormal diastolic function of the left ventricle: E/e'>15; if 15>E/e'>8, also need to include [a. Mitral valve blood flow spectrum (E/A280ms) or pulmonary venous blood Flow spectrum (Ard-Ad>30ms); b.LAVI>40ml/m2, LVMI>149d/m2 (male) />122g/m2 (female)]. Control group: 100-120 healthy people were screened according to the age and gender of the enrolled patients.
Exclusion criteria
Exclusion criteria: 1. Primary pulmonary hypertension; 2. Severe lung disease; 3. Unstable coronary artery disease, acute coronary syndrome; 4. Congenital heart disease; 5. Persistent arrhythmia; 6. Heart valve disease, severe heart valve calcification after heart valve surgery; 7. Severe kidney disease; 8. Severe liver disease; 9. Pacemaker surgery; 10. Pericardial disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left anterior descending branch;Left ventricular end diastolic diameter;Left ventricular end systolic diameter;Left ventricular end-diastolic volume;Left ventricular end systolic volume;Left ventricular ejection fraction;Peak velocity in early diastole;Peak velocity in late diastole;TR peak flow rate of tricuspid regurgitation;Early diastolic velocity of mitral valve annulus;receive operating characteristic, ROC;Consistency; | — |
Countries
china
Contacts
Public ContactYang Xi
People's Hospital of Shapingba District, Chongqing
Outcome results
None listed