Depression
Conditions
Interventions
Group One:Hybrid electric convulsive therapy based on individual clinical dynamic data monitoring
Sponsors
The Second People's Hospital of Huizhou
Eligibility
Sex/Gender
All
Age
16 Years to 25 Years
Inclusion criteria
Inclusion criteria: 1. Aged 16-25 years; 2. Hospitalized patients diagnosed as unipolar or bipolar depression according to ICD-10, with or without psychotic symptoms; 3. Sign the informed consent form; 4. Baseline Montgomery Depression Scale (MADRS)> 22 points or associated with suicide risk.
Exclusion criteria
Exclusion criteria: 1. Be pregnant; 2. Those who have participated in other related research within 30 days before enrollment; 3. Received ECT or rTMS treatment within 6 months before enrollment; 4. The previous poor effect on ECT; 5. In the history of psychoactive substance abuse; 6. There are contraindications related to ECT; 7. There is anesthesia risk such as cardiovascular disease; 8. There is a history of epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression screening scale(PHQ-9);Generalized Anxiety Disorder Scale(GAD-7);Montgomery Depression Scale(MADRS);Common Gateway Interface(CGI); | — |
Countries
China
Contacts
Public ContactXie Xinhui
The Second People's Hospital of Huizhou
Outcome results
None listed