Total Hip Replacement
Conditions
Interventions
Group E:RIPC after induction
Group L:RIPC 24 hours before surgery
Group T:RIPC 24 hours before surgery and after induction
Control group:Cuff is not inflated
Sponsors
The First People's Hospital of Lianyungang
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 65-80 years; 2. Patients undergoing elective hip replacement surgery; 3. The ASA score I-III, BMI 18-24 kg/m^2; 4. No obvious abnormalities in heart, lung, liver and kidney functions; 5. Clear understanding and volunteer to participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. The patient has severe vision and hearing impairment, or other reasons cannot communicate with the visitor; 2. Patients with degenerative diseases of the central nervous system; 3. Patients who have undergone heart or central nervous system surgery, or LVEF < 50%; 4. Limb movement disorders that affect neurocognitive function assessment; 5. The score of the Mini-Mental State Scale (MMSE) before operation cannot be matched and is lower than the minimum score of the corresponding education level (literacy <= 17 points, primary school <= 20 points, secondary school <=22 points, university <= 23 points); 6. Alcohol dependent patients; 7. Peripheral vascular disease (especially the stenosis or occlusion of the subclavian artery and upper extremity artery) or neurological disease affecting the sensory function of the upper extremity; 8. Patients with abnormal blood coagulation function; 9. Patients with difficulty in tracheal intubation; 10. Taking sedatives or antidepressants; 11. Withdrawal midway Experimenter.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Regional cerebral oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of delirium;Neuron specific enolase;Brain fatty acid binding protein; | — |
Countries
China
Contacts
Public ContactChen Ying
The First People's Hospital of Lianyungang
Outcome results
None listed