Lung cancer
Conditions
Interventions
Experimental group:the irradiation dose of 4GyE was given each time for 12 times
Control group:the irradiation dose of 3GyE was given each time for 16 times
Sponsors
Wuwei Tumor Hospital Heavy Ion Center
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Ability to follow the plan and sign an informed consent form; 2. There are complications that are not suitable for surgical resection or the patient refuses to undergo surgical treatment; 3. Between the ages of 18 and 80; patients with lung cancer diagnosed by bronchoscopy or lung biopsy; 4. Did not receive photon radiotherapy within half a year before this radiotherapy; 5. Exclude distant metastasis after imaging evaluation; 6. No acute severe infectious disease or active period of chronic infectious disease has been controlled; 7. The KPS score is greater than or equal to 60; 8. The general status of ECOG is scored 0-1; 9. The estimated survival period is greater than or equal to 12 months; 10. Sufficient organ function; 11. The location of the tumor needs to be able to meet the requirements of the radiation field layout; 12. The patient can lie supine or prone for more than 30 minutes in the position required for treatment.
Exclusion criteria
Exclusion criteria: 1. Complicated with other malignant tumors and has not been controlled; 2. The treatment area has received any radioactive seed implantation treatment; 3. The dose limit for organs at risk cannot reach the preset safe dose limit; 4. Metal prosthetic implants that may be interfered with by high-energy rays or may affect the dose of the radiation target area; 5. The physician believes that carbon ion radiotherapy will not benefit patients; 6. Combined with other diseases or other factors that may affect carbon ion therapy; 7. Accompanied by serious complications that may affect the progress of radiotherapy; 8. No capacity for civil conduct or limited capacity for civil conduct; 9. Circumstances considered by other doctors to be unsuitable to participate in clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dose limiting toxicity;Local control rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free survival;3 years overall survival; | — |
Countries
China
Contacts
Public ContactZhang Yanshan
Wuwei Tumor Hospital Heavy Ion Center
Outcome results
None listed