premature ovarian insufficiency
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Female patients aged between 25-40 years; 2. Havent received any other treatments in the last two months before enrollment; 3. Patients voluntarily participate in the study; 4. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who are pregnant or have a pregnancy plan in six months; 2. Patients with primary amenorrhea; 3. Congenital reproductive organ abnormalities; 4. Patients with internal diseases which can affect reproductive hormones, such as thyroid disease, SLE, etc.; 5. Patients with other serious internal diseases and mental diseases; 6. Patients with unilateral or bilateral oophorectomy; 7. Those who are unable to tolerate the tests or treatments during the course of this study; 8. Those who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| anti-Mullerian hormone, AMH;follicle stimulating hormone, FSH; | — |
Secondary
| Measure | Time frame |
|---|---|
| estradiol E2, E2;Luteinizing hormone, LH;FSH/LH;Menstrual condition;Kupperman index; | — |
Countries
China