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A Randomized Controlled Study of Ultrasound-Guided Microwave Ablation and Open Surgery for Benign Greater Thyroid Nodule

A Randomized Controlled Study of Ultrasound-Guided Microwave Ablation and Open Surgery for Benign Greater Thyroid Nodule

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045585
Enrollment
Unknown
Registered
2021-04-19
Start date
2021-04-19
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign thyroid nodule

Interventions

experimental group:Ultrasound-guided microwave ablation
control group:Open surgical treatment

Sponsors

Beijing Friendship Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.Aged >=18 years; 2.Maximum diameter of benign solid thyroid nodules >= 4cm; 3.Patients have neck pain, neck foreign body sensation and other discomfort, or neck enlargement affect the appearance; 4.Patients worried about malignant change of nodules, with greater psychological pressure; 5.Thyroid nodules were proved to be benign tumors by ultrasound-guided puncture biopsy and pathology.

Exclusion criteria

Exclusion criteria: 1.The large thyroid nodule is located posterior to the sternum; 2.Patients with coagulation dysfunction; 3.Patients with severe heart and lung diseases and poor control of severe hypertension; 4.Patients with severe neck skin infection foci; 5.Patients with contralateral vocal cord dysfunction; 6.The pathological results of puncture biopsy are malignant or inconclusive.

Design outcomes

Primary

MeasureTime frame
Nodular volume reduction rate;Effective rate of treatment;

Secondary

MeasureTime frame
Incidence of complications;Health-related quality of life score;

Countries

China

Contacts

Public ContactQian Linxue

Beijing Friendship Hospital, Capital Medical University

Qianlinxue2002@163.com+86 13311100999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026