Migraine and patent foramen ovale
Conditions
Interventions
different types of patent foramen ovale:Null
Sponsors
Beijing Tiantan Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years, no gender limits; 2. Patients who met the International Classification of Headache Disorders-3 criteria (ICHD-3), onset age =1 year, no more than one episode of tension headache per month is allowed; 3. Patent foramen ovale (with or without atrial septal defect, atrial septal tumor, etc.) was confirmed by transesophageal echocardiography; 4. Signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with other types of headache who cannot be identified or do not meet the diagnostic criteria for migraine; 2. Patients who previously diagnosed as patent foramen ovale or atrial septal defect and have received interventional occlusion; 3. Transesophageal ultrasound contraindications; 4. Patients who has a severe organic disease or tumor or other disease and is expected to survive less than 2 years; 5. Inability to complete follow-up due to geographical or other reasons (alcoholism, drug abuse or dementia and mental illness, etc.); 6. Contraindication of MRI examination; 7. Patients who have participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Migraine Related Scale HIT-6;Mood Scale PHQ-9;Mood Scale GAD-7;Migraine Related Scale MIDAS;Pittsburgh sleep quality index, PSQI;Headache diary;Dysfunction scale; | — |
Countries
China
Contacts
Public ContactJin Ze'ning
Department of Cardiology and Macrovascular Disease, Beijing Tiantan Hospital,Capital Medical University
Outcome results
None listed