Effects of early versus delayed weight-bearing on postoperative outcomes after microfractures of osteochondral lesions of the talus: a randomized, controlled, non-inferiority study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100045507

Enrollment

Unknown

Registered

2021-04-18

Start date

2021-04-17

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteochondral lesions of the talus

Interventions

Experimental group:Early postoperative weight-bearing

Control group:Delayed postoperative weight bearing

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18-60 years, male or female; 2.Clinically confirmed talus cartilage injury, accompanied by pain, is ineffective after conservative treatment for more than 3 months; 3.Preoperative magnetic resonance evaluation indicated that the lesion range of talus cartilage was less than 100mm^2; 4.Patients underwent arthroscopic microfracture surgery; 5.Patients are willing and able to comply with the planning, rehabilitation, nursing, and follow-up protocols of this study.

Exclusion criteria

Exclusion criteria: 1.Previous surgery on the affected foot and ankle; 2.The patient has diabetes; 3.Has an autoimmune disease and is in an active stage; 4.Mental disorder or any mental disorder that affects the patient's behavior.

Design outcomes

Primary

Measure	Time frame
AOFAS ankle - hind foot function score;	—

Secondary

Measure	Time frame
VAS score of pain;	—

Countries

China

Contacts

Public ContactSong Weidong

Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University

songsz999@163.com+86 13710666839

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026