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The clinical significance of arterial oxygenation by removing destroyed lung: an adaptive randomized controlled trial

The clinical significance of blood oxygenation by removing destroyed lung: an adaptive randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045486
Enrollment
Unknown
Registered
2021-04-17
Start date
2021-04-16
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

destroyed lung

Interventions

Surgery group:Destroyed Lung Surgical removal
Internal Medicine Treatment Group:Conservative Treatment

Sponsors

The Third Hospital of Zhangzhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The subject has subjective breathing difficulties or dyspnea; 2. The extent of the damaged lung; the subject's ipsilateral lung is less than half of the lung damaged. If lung fissure can be identified on CT, at least no more than two lung lobes can be damaged in the right lung, and no more than one lung lobe can be damaged in the left lung; 3. The age of the subjects ranges from 18 to 80 years old; 4. The subject is selected as the result of the preliminary screening of lung damage based on CT scan, regardless of the cause of the lung damage, disease stage or whether the subject has received treatment in the past; 5. PaO2 < 90mmHg during screening.

Exclusion criteria

Exclusion criteria: 1. Females with pregnancy or breast breeding are excluded. 2. Acute heart dysfunction (BNP > 2000). 3. Acute coronary syndrome. 4. Blood clotting diseases including thrombosis and stroke. 5. Circulation problems which prevent blood gas drawing in the radial artery. 6. Renal failure or those with dialysis. 7. Severe anaemia (haemoglobin < 6 g/dL).

Design outcomes

Primary

MeasureTime frame
Partial Pressure of Oxygen;

Secondary

MeasureTime frame
Arterial oxygen saturation;Arterial Saturation of Oxygen (6MWT);Maximum expiratory volume in the first second of expiration(FEV1);Body surface area;Resolved Symptoms;

Countries

China

Contacts

Public ContactYe Huilong

The Third Hospital of Zhangzhou

T.Wang-63@sms.ed.ac.uk+86 18950027555

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026