Effect of preoperative medication with dexmedetomidine on stress induced by general anesthesia

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100045458

Enrollment

Unknown

Registered

2021-04-15

Start date

2021-05-07

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuosurgery

Interventions

Control group:without preoperative medication

Dexmedetomidine group:Preoperative medication with dexmedetomidine

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: General anesthesia with tracheal intubation, age from 18 to 70, male or female.

Exclusion criteria

Exclusion criteria: 1.Severe organs dysfunction; 2.Sinus bradycardia; 3.Pituitary tumor, hormones abnormal or oral hormones; 4.Severe OSA; 5.Sensitive to dexmedetomidine; 6.Multiple operations(>=3).

Design outcomes

Primary

Measure	Time frame
Sedation score;Corticotropin;Cortisol;	—

Countries

China

Contacts

Public ContactGao Jie

The First Affiliated Hospital of Kunming Medical University

xiongjun107@mail.ccmu.edu.cn+86 18513137381

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026