Study on fetal-gut-pulmonary axis microecology and lung injury in preterm infants

Study on fetal-gut-pulmonary axis microecology and lung injury in preterm infants based on Toll receptor 4

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100045444

Enrollment

Unknown

Registered

2021-04-15

Start date

2021-08-01

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung injury

Interventions

Bronchopulmonary dysplasia (BPD) group:Null

Non-bronchopulmonary dysplasia (non-BPD) group:Null

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Premature infants (gestational age <37 weeks) admitted to the neonatal intensive care unit (NICU) of our hospital from June 2021 to December 2021 are divided into bronchopulmonary dysplasia (BPD) and non-bronchiopulmonary dysplasia (non-BPD) .

Exclusion criteria

Exclusion criteria: 1. Congenital malformations (including complicated congenital heart disease and lung development malformations); 2. Inherited metabolic diseases; 3. Chromosomal diseases; 4. Family members who do not agree to participate in the study.

Design outcomes

Primary

Measure	Time frame
Stool Microecology;Microecology of Airway secretion;Placental microecology;Toll receptor 4;	—

Countries

China

Contacts

Public ContactZhang Lei

Chengdu Women's and Children's Central Hospital

534167313@qq.com+86 13679023315

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026