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Efficacy of sensory nerve reconstruction in orofacial defect repair

Efficacy of sensory nerve reconstruction in orofacial defect repair

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045425
Enrollment
Unknown
Registered
2021-04-14
Start date
2021-06-01
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

head and neck tumors

Interventions

Control group:End-to-end or end-to-side anastomosis of the free skin flap with the nerve in the recipient area
Experimental group:Sensory free flap transplantation

Sponsors

West China Stomatological Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 90 Years

Inclusion criteria

Inclusion criteria: 1.Age and sex of subjects are not limited, while tumor can occur in tongue, cheek, mandibular gum or mouth floor, and T and N staging of carsinoma is not limited. 2. Subjects who undergoing fibula free flap reconstruction of the head and neck, including the subjects who undergoing primary or secondary reconstruction. 3. Subjects who volunteer to participate and sign the "Informed Consent Form of Patients".

Exclusion criteria

Exclusion criteria: 1. Subjects who may require a return during hospitalization will be excluded unless the second operation is completely unrelated to the flap. 2. Subjects who could not successfully dissection the recipient nerve during the operation or the recipient nerve was invaded by malignant tumor and needed to be removed; 3. Subjects with persistent coma, unclear consciousness and communication barriers after surgery; 4. Subjects with less than one year of postoperative survival or no follow-up.

Design outcomes

Primary

MeasureTime frame
two point discrimination sense;algesthesia;thermo-esthesia;

Countries

China

Contacts

Public ContactChen Su

West China Stomatological Hospital of Sichuan University

815386702@qq.com+86 18715850078

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026