anesthesia
Conditions
Interventions
control group:propofol
Sponsors
Yibin Second People's Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1.Age 18-65, gender unlimited; 2.American anesthesiologist grade (ASA) I-II; 3.Patients who underwent painless gastroscopy and/or colonoscopy treatment at selected time; 4.Body mass index (BMI) >= 18 and <= 30kg/m2; 6.Understand the purpose of this study and volunteer to participate in this study.
Exclusion criteria
Exclusion criteria: 1.Patients with contraindications to general anesthesia or with previous history of anesthesia accidents; 2.People with known or suspected allergy or contraindination to propofol injection, cyclopofol injection excipients, opioids, muscle relaxants, etc.; 3.Patients with acute upper respiratory tract infection, asthma attack, or acute severe laryngeal disease; 4.Complicated craniocerebral loss, intracranial hypertension, stroke, cerebrovascular accident history, etc.; 5.Resrespiratory insufficiency, obstructive pulmonary disease, presence of difficult airway, or tracheal intubation difficulty (modified Markov score grade III or IV); 6.Uncontrolled hypertension, hypotension and diabetes; 7.Severe arrhythmia, heart failure, unstable angina pectoris, myocardial infarction, etc.; 8.Severe liver dysfunction or severe renal insufficiency; 9.A history of alcohol abuse or drug dependence; 10.Abuse or long-term use of narcotic, sedative and analgesic drugs; 11.People with a previous history of mental illness; 12.Screening participants who had participated in any drug clinical trials within 1 month prior to screening; 13.Pregnant and lactating women;Fertile women or men were reluctant to use contraception throughout the trial;Subjects (including male subjects) who plan to become pregnant within 1 month after the trial; 14. Subjects who have any other factors considered by the Investigator to be inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of successful anesthesia induction;Time of gastroscopy;Success rate of gastroscopy;Duration of endoscopy/colonoscopy;Fully awake duration;Length of room separation;study the use of drugs and alternative medicines;Satisfaction evaluation of sedation/anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events: incidence of adverse events, serious adverse events and adverse reactions;Vital signs: including RR, HR, SpO2, SBP, DBP, MAP;Laboratory examination: blood routine, urine routine, biochemical examination, electrocardiogram;Evaluation of injection pain (VRS scale);Incidence of cough and body movement in diagnosis and treatment; | — |
Countries
China
Contacts
Public ContactChen Xingqu
Yibin Second People's Hospital
Outcome results
None listed