Cognitive Decline
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged 65-80 (65-75 in priority) years; 2.mild cognitive impairment:21=MMSE=26,and one of the following two tests (1) AD8=2 or(2)Digit Span(backward)<4 points
Exclusion criteria
Exclusion criteria: 1. Subjects who are unable to complete the intervention activities, such as those with extreme weakness, active epilepsy, serious liver disease or renal disease, mental illness and cancer, etc. 2. Be under treatment for cognitive function improvement or rehabilitation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| executive function composite score;Global cognitive function composite score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activity of daily living;Instrumental activity of daily living;SPPB test (including 5 sitting up test, tandem standing balance test, 2.44m walk test);Mini-mental State Examination (MMSE);Cognitive impairment self-rating scale;Trail Marking Test;Digit Span Test;Verbal fluency test;Digit Symbol test;Clock Drawing Test;change in level of CVDs risk factors;GDS-15 score;sleep dysfunction;fall incidence; | — |
Countries
China
Contacts
Chinese Center for Disease Control and Prevention