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Effects of continuous end-expiratory carbon dioxide monitoring on adverse outcomes after spontaneous circulation recovery in patients with nosocomial cardiac arrest: a randomized controlled trial

Effects of continuous end-expiratory carbon dioxide monitoring on adverse outcomes after spontaneous circulation recovery in patients with nosocomial cardiac arrest: a randomized controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045311
Enrollment
Unknown
Registered
2021-04-10
Start date
2021-04-20
Completion date
Unknown
Last updated
2021-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

In-hospital Cardiac Arrest

Interventions

Control group:Conventional therapy
Experimental group:Continuous monitoring of End-Tidal Carbon Dioxide and guidance on the use of salvage drugs

Sponsors

Qilu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients must meet all the following criteria to be enrolled: 1.Aged >=18 years, male or female; 2.In-hospital cardiac arrest patients who reach ROSC after cardiopulmonary resuscitation, with the maintenance duraion longer than 30 minutes; 3.The patient authorized the client to sign the informed consent.

Exclusion criteria

Exclusion criteria: Any patient who meets any of the following criteria cannot be included in the group: 1.The duration of ROSC less than 30 minutes; 2.Patients who have suffered out of hospital cardiac arrest with successful resuscitation , and fail to experience cardiac arrest again in the hospital; 3.Those considered by the researcher to be unsuitable to participate in this research.

Design outcomes

Primary

MeasureTime frame
28 day mortality rate;

Secondary

MeasureTime frame
28d mortality in patients with ST-segment elevation myocardial infarction and ROSC with malignant arrhythmiaMI and malignant arrhythmia;Incidence of various complications;Brain functional classification score;Fluctuations in blood pressure, heart rate, blood oxygen saturation, ETCO2, blood lactic acid, myocardial injury markers, inflammation indicators, etc.;

Countries

China

Contacts

Public ContactBian Yuan

Qilu Hospital of Shandong University

29207234@qq.com+86 18560083065

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026