eczema of infants
Conditions
Interventions
Intervention group:Daily quantitative administration of bifidobacterium lactis BB12 probiotic oil drops (6 drops each time, once a day)
Control group:Daily ration of oil drops of lactobacillus bifidobacterium BB12 probiotics
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
0.1 Years to 1 Years
Inclusion criteria
Inclusion criteria: 1.Meeting Williams diagnostic criteria for atopic dermatitis: (3 or more major criteria plus 3 minor criteria); 2.Aged 30 days - 12 months; 3.Full-term infants, 37<= gestational age <42 weeks with birth weight between 2500-4000 g; 4.No antibiotics, probiotics, or other medications or foods were given within 2 weeks; 5.Willing to participate the treatment and make the regular visit; 6.Willing to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1.With metabolic disease, genetic disease or chronic disease; 2.Participating another clinical trial; 3.During the follow-up period, other diseases such as bronchitis and pneumonia need to be treated with antibiotics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SCORAD Index;Gut microbial compositions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight and height;Personal quality of life;Family life impact index; | — |
Countries
China
Contacts
Public ContactJia Jie
Shanghai Jiaotong University School of Medicine
Outcome results
None listed