esophageal cancer
Conditions
Interventions
Intervention group:Oral Nutrition supplement
Control group:None
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18-75 years old, male or female; 2.Preoperative histopathological diagnosis of thoracic esophageal carcinoma (squamous cell carcinoma, adenocarcinoma, adenosquamous cell carcinoma) and clinical stage CT1-3N0M0; 3.ECOG score of 0 or 1; 4.Patients with expected survival >=12 months; 5.No operation contraindication was found in preoperative organ function examination; 6.McKeown MIE and manual cervical anastomosis were performed; 7.Neutrophils >= LNL; hemoglobin >= 10g/dl; platelets >=100 x 10^9/L; cbtotal bilirubin = 55 mL/min. 8.Subject must understand and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Severe cardiovascular diseases, including uncontrollable hypertension (BP >= 160 / 95mmhg), unstable angina pectoris, history of myocardial infarction in the past 6 months, congestive heart failure > NYHA II, severe arrhythmia and pericardial effusion; 2.Exploratory operation or positive margin were performed; 3.Hypersensitivity to the contents of oral nutrient solution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight loss ratio;Body Mass Index;Skeletal muscle mass and index in extremities;Grip strength and phase Angle;Nutrition-related blood parameters;Incidence of postoperative complications;Intestinal microflora community differences;Living quality; | — |
Countries
China
Contacts
Public ContactLi Yin
Department of Thoracic Surgery, Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed