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Effects of dexmedetomidine pretreatment and posttreatment on renal function during Living Relative Renal Transplantation

Effects of dexmedetomidine pretreatment and posttreatment on renal function during Living Relative Renal Transplantation

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045246
Enrollment
Unknown
Registered
2021-04-09
Start date
2021-04-01
Completion date
Unknown
Last updated
2021-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Transplantation

Interventions

Group D1:dexmedetomidine pretreatment
Group D2:dexmedetomidine posttreatment

Sponsors

The First Affiliated Hospital Of USTC
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 69 Years

Inclusion criteria

Inclusion criteria: 1. Donor: (1) Aged 20-69 years, no gender limits; (2) ASA I-II level; (3) BMI 18.5-28 kg/m^2; (4) The heart, lung, liver and blood coagulation functions are not abnormal; (5) No history of allergy to anesthetics; (6) Volunteers voluntarily sign written informed consent. 2.Receptors: (1) Aged 20-69 years, both male and female; (2) ASA III~VI level; (3) BMI 18.5-28 kg/m^2; (4) The heart, lung, liver and blood coagulation functions are not abnormal; (5) No history of allergy to anesthetics; (6) Volunteers voluntarily sign written informed consent.

Exclusion criteria

Exclusion criteria: 1. Donor: (1) Those who have suffered from any serious clinical disease in the past or currently; (2) A history of allergies to drugs, food or other substances; (3) Uncontrolled hypertension; (4) Those who may not be able to complete the study due to other reasons or the researcher thinks they should not be included. 2. Receptor: (1) Past or present suffering from any serious clinical disease other than the urinary system; (2) A history of allergies to drugs, food or other substances; (3) Those who may not be able to complete the study due to other reasons or the researcher thinks they should not be included.

Design outcomes

Primary

MeasureTime frame
Blood creatinine;Blood urea nitrogen;Cystatin C;C reactive protein;Urine volume;

Countries

China

Contacts

Public ContactXie Yanhu

Department of Anesthesiology, The First Affiliated Hospital Of USTC

xyh200701@sina.cn+86 13956013081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026