Induction of general anesthesia in gynecological surgery
Conditions
Interventions
Experimental group:Cyclopofol injection
Sponsors
Sichuan Provincial Women's and Children's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years, no gender limitation; 2. American Society of Anesthesiologists (ASA) Grade I-II; 3. Patients requiring endotracheal intubation general anesthesia for elective surgery; 4. Body mass index (BMI) >=18 kg/m^2 and =10 and = 95% when breathing air; Systolic blood pressure (SBP) >=90 mmHg and = 60mmHg and =55 and <=100 beats/min; 6. Can understand the process and method of this study, and volunteer to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to general anesthesia or with previous history of anesthesia accidents; 2. Patients who are known or suspected to be allergic or contraindicated to propofol injection, cyclopofol injection excipients, benzodiazepines, opioids, muscle relaxants, etc.; 3. Patients with complicated craniocerebral loss, intracranial hypertension, stroke, unstable angina pectoris or myocardial infarction; 4. Resrespiratory insufficiency, obstructive pulmonary disease, presence of difficult airway, or judged tracheal intubation difficulty (modified Markov score grade III or IV); 5. Uncontrolled diabetes or hypertension; 6. With severe liver dysfunction or severe renal insufficiency; 7. With a history of alcohol abuse or drug dependence; 8. Abuse or long-term use of narcotic, sedative and analgesic drugs; 9. Patients with a history of mental illness; 10. Patients who had participated in any drug clinical trial within 1 month before screening; 11. Pregnant and lactating women;Fertile women or men were reluctant to use contraception throughout the trial;Subjects (including male subjects) who plan to become pregnant within 1 month after the trial; 12. Patients who, in the opinion of the Investigator, have any other factors that are not suitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of anesthesia induction;Duration of successful anesthesia induction;Length of disappearance of eyelash reflex;Changes of bispectral index ; | — |
Countries
China
Contacts
Public ContactChen Benzhen
Sichuan Provincial Women's and Children's Hospital
Outcome results
None listed