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basic and clinical study on prognostic factors of young PDR patients treated with 25G minimally invasive vitrectomy

basic and clinical study on prognostic factors of young PDR patients treated with 25G minimally invasive vitrectomy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100045206
Enrollment
Unknown
Registered
2021-04-08
Start date
2021-04-08
Completion date
Unknown
Last updated
2021-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Proliferative diabetic retinopathy

Interventions

Youth group:25G minimally invasive vitrectomy
middle aged and elderly group:25G minimally invasive vitrectomy

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients meet the diagnostic criteria of PDR, that is, one or more of the following changes: neovascularization, vitreous hemorrhage or preretinal hemorrhage. 2. It conforms to the indications of vitrectomy, that is, vitreous hemorrhage (VH), progressive fibrovascular proliferation (FVP), traction macular thickening and macular hole, traction retinal detachment (TRD), and traction rhegmatogenous retinal detachment (TRRD). 3. Aged over 18 years, no gender limits. 4. Informed consent can be obtained and patients participate in the experiment voluntarily.

Exclusion criteria

Exclusion criteria: 1. Patients with retinal vein occlusion, retinal artery occlusion, ocular diseases caused by trauma, etc. 2. Ophthalmic surgery has been perfo2022rmed recently. 3. Patients are unable to follow up on time in accordance with the doctor's advice.

Design outcomes

Primary

MeasureTime frame
blood glucose;duration of diabetes;blood pressure;HbA1c;urea;creatinine;preoperative retinal breaks;number of preoperative retinal detachment quadrants;preoperative visual acuity;preoperative intraocular pressure;surgical indications;preoperative laser range;preoperative anti-VEGF therapy;duration of operation;fibrovascular proliferation membrane grade;severity score of diabetic retinopathy;intraoperative complications;intraoperative electric coagulation;laser;vitreous tamponade;postoperative visual acuity;postoperative intraocular pressure;DME occurrence and treatment;retinal reattachment;early and late bleeding conditions;NVG occurrence;ERM occurrence;second operation;VEGF concentration in aqueous humor and vitreous;CTGF concentration in aqueous humor and vitreous;TNF-a concentration in aqueous humor and vitreous;—

Countries

China

Contacts

Public ContactHan Jindong

Tianjin Medical University Eye Hospital

djindonghan@126.com+86 13043234240

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026