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Effect of precondition of one lung ventilation on oxygenation index of patients during operation

Effect of precondition of one lung ventilation on oxygenation of patients during operation

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045203
Enrollment
Unknown
Registered
2021-04-08
Start date
2021-03-30
Completion date
Unknown
Last updated
2021-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Control group:One-lung ventilation is performed directly after the position is placed and repositioned, and both lungs are ventilated after the lung recruitment is completed.
Experimental group:After the dual-chamber bronchus is inserted and positioned, perform one-lung ventilation for 2 minutes, two-lung ventilation for 2 minutes, one-lung ventilation for 4 minutes, and t

Sponsors

The First Affiliated Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Thoracoscopic radical resection of lung cancer (non-small cell lung cancer) was performed electively; 2. Aged 18-65 years, ASA grade I-II; 3. The BMI: 16 - 25 kg/m^2; 4. The preoperative pulmonary function examination was basically normal.

Exclusion criteria

Exclusion criteria: 1. People with a history of bronchial asthma and high airway responsiveness; 2. Intraoperative thoracotomy patients; 3. Patients with intraoperative massive bleeding; 4. Patients with cerebrovascular diseases; 5. Death during or 48 hours after surgery; 6. History of chest surgery, radiotherapy or chemotherapy; 7. With serious heart, liver or kidney diseases, 8. History of mental illness; 9. Long-term medication history.

Design outcomes

Primary

MeasureTime frame
oxygenation index;

Countries

China

Contacts

Public ContactFang Jieyu

The First Affiliated Hospital of Sun Yat-Sen University

13660121136@163.com+86 13660121136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 1, 2026