cardiopulmonary bypass in cardiac surgery
Conditions
Interventions
A group:CPB cardiac surgery was performed under combined anesthesia of propofol-desflurane-dexamete
B group:CPB cardiac surgery was performed mainly under intravenous anesthesia with propofol-dexamethasone
Sponsors
The First hospital of China Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age between 16 and 60 years; 2.An ASA score of II-III; 3.Patients in open cardiac surgery under cardiopulmonary bypass.
Exclusion criteria
Exclusion criteria: 1.Patients with a history of Parkinson's, epilepsy, psychosis, Alzheimer's disease or myasthenia gravis before surgery; 2.Patients with a history of delirium or cognitive impairment; 3.Severe liver and kidney dysfunction, hypoalbuminemia ; 4.A visual and hearing impairment; 5.People unable to communicate normally due to language barriers, coma, dementia, sequelae of cerebrovascular disease, etc. before surgery; 6.Previous neurosurgery operation history; 7.Previous drug abuse; 8.Patients considered unsuitable for the study by the investigator; 9.Patients who do not agree to participate in this experiment; 10.More than 24 hours after operation with ventilator assistance (without extubation), cardiopulmonary bypass repeated transfer and transfer time exceeds 2 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS);Richmond Agitation-Sedation Scale (RASS);ICU Ambiguity Assessment Scale (CAM-ICU);Mini-mental State Examination (MMSE); | — |
Countries
China
Contacts
Public ContactTian Ayong
The First Hospital of China Medical University
Outcome results
None listed