oral squamous cell carcinoma
Conditions
Interventions
Gold Standard:Pathologic diagnosis
Index test:Nomogram model
Sponsors
Beijing Stomatological Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: Experiment 1 1.Age: First visit to the Department of Oral and Maxillofacial Head and Neck Oncology of our hospital and received radical surgical treatment when he/she was 30-75 years old at the time; 2.Gender: Men and women are not limited; 3.Oral squamous cell carcinoma was reported by postoperative pathology in the primary patient; 4.Tumor sites: tongue body, cheek mucosa, upper and lower gingiva, mouth floor and hard palate mucosa, clinical staging: CT1-2N0M0 (based on enhanced CT or MRI examination) was admitted to our hospital for oral and maxillofacial surgery and received radical surgical treatment. Experiment 2 1.Age: 30-75 years old; 2.Gender: Men and women are not limited; 3.Oral squamous cell carcinoma was confirmed by preoperative pathological biopsy in all the first patients; 4.Tumor sites: tongue body, buccal mucosa, upper and lower gingiva, mouth floor and hard palate mucosa, clinical staging: CT1-2N0M0 (based on enhanced CT or MRI examination); 5.Excluding distant metastases by chest radiographs and/or abdominal B-ultrasound, enhanced CT and/or MRI and/or PET/CT examinations in suspicious cases were used to assist diagnosis.
Exclusion criteria
Exclusion criteria: Experiment 1 1.Complete clinical data cannot be obtained;Histopathological specimens are not available or cannot be evaluated; 2.Complete follow-up data of neck metastases were not available; 3.Patients who had received radical surgery or radiotherapy in other hospitals before hospitalization in our hospital; 4.Other circumstances that the researcher considers inappropriate to participate in the study. Experiment 2 1.Refuse to accept the treatment plan; 2.The patient is expected to be unable to complete the follow-up; 3.Patients with poor general condition and unable to receive treatment: Routine examination on admission, such as three routine tests, blood biochemical examination, electrocardiogram, chest radiograph, etc., indicated surgical contraindination, including but not limited to Hb 133µmol/L, etc., and preoperative treatment for abnormal indicators failed and follow-up treatment was not possible; 4.Recurrent patients: including those whose tumor was not completely resected for the first time in our hospital or other hospitals, and who had been treated with surgery or radiotherapy for the purpose of radical cure in other hospitals; 5.Patients who did not receive surgical treatment for the purpose of radical tumor resection after admission to our hospital, such as those who were transferred to other hospitals for treatment after biopsy; 6.Other situations that the researcher considers not suitable for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor infiltrating cells;Depth of invasion;The worst way to invade a tumor;Number of tumor buds;Pathology grade;Neurological invasion assessment;SEN, SPE, ACC, AUC of ROC, PPV, NPV; | — |
Countries
China
Contacts
Public ContactFeng Zhien
Beijing Stomatological Hospital, Capital Medical University
Outcome results
None listed