postoperative delirium
Conditions
Interventions
Sponsors
Ruijin Hospital Luwan Branch, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Patients with gastrointestinal surgery aged =50 years; 2. I=ASA=III, no gender limits.
Exclusion criteria
Exclusion criteria: 1. Cardiac ejection fraction < 40%; 2. Heart rate < 50 beats/min, non-first-grade atrioventricular block arrhythmia; 3. Severe liver and kidney dysfunction; 4. Patients suffering from chronic pain disorder, dementia, or drug addiction; 5. Use antipsychotics, antidepressants, beta-blockers, antiarrhythmic drugs, or digoxin within one week before surgery; 6. Patients who are allergic to dexmedetomidine; 7. Patients who have taken any sedative, hypnotic, analgesic, or psychotherapeutic drugs before induction of anesthesia; 8. Past history of alcoholism or drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| serum brain-derived neurotrophic factor; | — |
Countries
China
Contacts
Public ContactSun Jihui
Luwan Branch of Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed