Postoperative delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Elderly patients undergoing elective thoracoscopic lobectomy under general anesthesia; 2. Aged > 60 years, weight 40-90kg, gender is not limited; 3. ASA Grade I-III, cardiac function Grade I-III; 4. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe hypertension, diabetes, pulmonary disease, liver and kidney insufficiency, heart disease or arrhythmia with poor control and Hb<75g/L; 2. Preoperative neuropsychiatric system disease, use of sedatives or antidepressants, alcohol abuse or drug dependence; 3. Patients with preoperative MMSE scores lower than the corresponding threshold; 4. Patients with hearing and visual impairment; 5. The use of dexmedetomidine is contraindicated with severe bradycardia or conduction block Disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean cerebral oxygen saturation;incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| changes in hemodynamics;extubation time;bed time;pull out time of thoracic guide tube;the length of time;the incidence of postoperative pulmonary complications; | — |
Countries
China
Contacts
Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University