post-stroke depression
Conditions
Interventions
genetic typing:none
Sponsors
Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged over 18 years, with acute phase of stroke (Including a first-ever event or a recurrent stroke); 2. Stroke is defined according to WHO criteria: sudden focal or generalized neurological dysfunction lasting over 24h, including ischemic and hemorrhagic stroke (also including cerebral infarction patients with complete remission after thrombolytic therapy); 3. Patients admitted to hospital with 14 days of stroke onset; 4. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. Non-vascular causes of brain dysfunction (primary brain tumormetastatic encephaloma, subdural haematoma, Postseizure paralysiscerebral trauma, et al.); 2. Past history of depression, dementia and psychiatric disorders; 3. Disable on vision, hearing, language; consciousness and comprehension deficits (MMSE<15) , unable to ensure valid assessments; 4. Unable to complete the 1 year follow-up; 5. Transient ischemic attack and Subarachnoidal hemorrhage; 6. Other existing neurological disease (Parkinsons disease, epilepsy, et al).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIH Stroke Scale, NIHSS;HAMD-17; Modified Rankin Scale;Mini Mental State Examination;PHQ-15;BI index;PHQ-9;DNA; | — |
Countries
China
Contacts
Public ContactZhu Suiqiang
Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed