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The efficacy of unfractionated heparin in patients with sepsis: a single-center retrospective study

The efficacy of unfractionated heparin in patients with sepsis: a single-center retrospective study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100045167
Enrollment
Unknown
Registered
2021-04-07
Start date
2021-04-10
Completion date
Unknown
Last updated
2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

heparin group:unfractionated heparin treatment
control group:without anticoagulation treatment

Sponsors

Rujin Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years and 10mg/L and D-Dimer > 5mg/L.

Exclusion criteria

Exclusion criteria: 1. Platelet count < 30 x 10^9/L or Fg < 150mg/dl; 2. Pregnant or lactation or with blood disease or immunosuppression status; 3. Complications with bleeding risks(e.g, severe brain injury, cerebral aneurysm, arteriovenous malformation, bronchiectasis, peptic ulcer, liver cirrhosis, hemorrhoids etc.); 4. Under anticoagulation or antiplatelet treatment; 5. Severe trauma or within 24h of surgery.

Design outcomes

Primary

MeasureTime frame
28d mortality rate;—

Secondary

MeasureTime frame
disease severity score;heparin dose;disseminated intravascular coagulation;—

Countries

China

Contacts

Public ContactMao Enqiang

Department of Emergency, Rujin Hospital, Shanghai Jiao Tong University School of Medicine

maoeq@yeah.net+86 13501747906

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026