disorder of consiousness
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged >18years; 2. Subacute patients diagnosed as DOC by CRS-R; 3. No nerve stimulating drugs were used within 48 hours before enrollment; 4. No neuromuscular blocker was used within 24 hours before enrollment; 5. No facial or ear pain, no recent ear trauma, no metal implants, including pacemakers, no pregnancy.
Exclusion criteria
Exclusion criteria: 1. Personal or family history of epileptic seizures, history of cardiovascular disease, history of developmental neurological or psychiatric disease; 2. Untreated brain edema; 3. Metal implants in the body; 4. Unstable vital signs; 5. MRI scan contraindications: such as claustrophobia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Behavior scale;Electroencephalogram; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional magnetic resonance;PET-glucose metabolism;telomere, proteins; | — |
Countries
China
Contacts
Hangzhou Normal University/Qianjiang College