Analgesic effect of L4 level anterior quadratus lumborum block in open hysterectomy: a randomized, double-blind, placebo-controlled, single center clinical trial

Mechanism of anterior quadratus lumborum block and its application in gynecological surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100045157

Enrollment

Unknown

Registered

2021-04-07

Start date

2021-04-10

Completion date

Unknown

Last updated

2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

open hysterectomy

Interventions

quadratus lumborum block group:bilateral L4 level quadratus lumborum block with 20 ml of ropivacaine 0.375%

control group:bilateral L4 level quadratus lumborum block with 20 ml of normal saline

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1.Aged 45-65 years, body mass index 18-25 kg/m2; 2.ASA classification I-II level; 3.Able to fully understand the research content.

Exclusion criteria

Exclusion criteria: 1.Abnormal heart, liver and kidney function, allergy to local anesthetics; 2.Contraindications of quadratus lumbar muscle block; 3.Chronic pain or receiving chronic pain treatment.

Design outcomes

Primary

Measure	Time frame
sufentanil consumption 24 hpost-surgery;	—

Secondary

Measure	Time frame
remifentanil comsuption during surgery;Time for first self-controlled analgesia after operation;NRS scores after surgery;Heart rate, mean arterial pressure;lower limb muscle strength;nausea and vomiting after surgery;timing of first flatus and defecation;	—

Countries

China

Contacts

Public ContactWu Jin

Department of Anesthesiology, The Affiliated Hospital of Jiangsu University

wujin914@hotmail.com+86 15905281553

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026