Liver fibrosis
Conditions
Interventions
Gold Standard:Liver biopsy.
Index test:FibroTouch, LSM.
Sponsors
The Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Aged >= 18 years; 2.Diagnosis of chronic viral hepatitis B.
Exclusion criteria
Exclusion criteria: 1.Exclude situations that may affect the accuracy of liver stiffness value (FSM): that is, any of the following situations cannot be included: (1) ALT >= 5 x ULN (5 times the upper limit of normal); (2) Total bilirubin >= 17.1µmol/L; (3) BMI > 30kg/m2; (4) Extrahepatic cholestasis (B-ultrasound indicates extrahepatic bile duct dilation and serum ALP >= 1.5 x ULN and GGT >= 3 x ULN); (5) Excessive alcohol intake (drinking alcohol 1 week before the examination); 2.Acute kidney injury (may affect urinary IGFBP7 concentration); 3.Pregnancy; 4.A history of alcohol or narcotic drug abuse, drug use, or a history of mental illness (such as schizophrenia, obsessive-compulsive disorder, depression), confrontational personality, bad motivation, suspiciousness or other emotional or intellectual problems, etc. may affect the knowledge of participating in this research Effectiveness; 5.Patients who cannot cooperate with the relevant inspections of this project and do not agree to sign an informed consent form; 6.The required information is incomplete.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Accuracy;Area under the curve, AUC; | — |
Countries
China
Contacts
Public ContactHan Huanqin
The Affiliated Hospital of Guangdong Medical University
Outcome results
None listed