Diabetes and metabolic related diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.According to the standard diagnosis criteria of diabetes published by WHO and IDF in 1999; 2.According to the standard of obesity Obesity Task Force established in 2001, BMI >= 28k / m2.
Exclusion criteria
Exclusion criteria: 1.Patients with severe diabetes complications, such as leg ulcers, severe kidney injury, severe neurological disease, severe retinopathy, etc.; 2.Patients have taken antibiotics for 3 days or more in the past 3 months; 3.Alcoholism (drinking more than 5 times per week, with an average of more than 50 g of white wine or 500g of chinese rice wine or 5 bottles of beer each time); 4.Patients suffer from a serious mental disorder in the past 6 months; 5.Patients have thyroid dysfunction due to medical treatment for the following diseases in the past 3 months: cholecystitis, gastrointestinal ulcer, urinary tract infection, acute pyelonephritis, cystitis, hyperthyroidism, etc.; 6.Patients had undergone gastrointestinal surgery, except appendicitis and hernia surgery; 7.Patients with chronic and persistent hepatitis, cirrhosis and other serious liver diseases or hepatitis B virus surface antigen (HBsAg) positive accompanied by abnormal liver function (serum alanine aminotransferase and aspartate aminotransferase are 2.5 times of the normal value); 8.Patients suffer from abnormal pituitary function; Severe organic diseases such as cancer, myocardial infarction and stroke; Infectious diseases such as tuberculosis and HIV/AIDS; 9.Weight loss in the past 3 months by drug method (such as: fluorophenylpropanol, thyroid hormone, progesterone, laxatives and traditional Chinese medicine) or surgical methods; 10.Patients can not take care of themselves, can not clearly recall, answer questions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| routine blood;routine urine;blood lipids;blood sedimentation;liver biochemical test;thyroid function (TSH, FT3, FT4);insulin;C-Peptide; serum glycosylated hemoglobin; | — |
Countries
China
Contacts
Endocrine and Metabolic Diseases Hospital of Shandong First Medical University