A prospective study of CT-guided single-needle ''synchronous biopsy + radical microwave ablation'' in the treatment of early lung cancer in elderly and high-risk patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100045133

Enrollment

Unknown

Registered

2021-04-07

Start date

2021-04-02

Completion date

Unknown

Last updated

2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Research Group:synchronous biopsy + radical microwave ablation

Control Group:Stereotactic radiotherapy

Eligibility

Sex/Gender

All

Age

70 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Single lesion, clinically considered as early lung cancer; 2.No distant metastasis or lymph node metastasis confirmed by PET-CT, head MR or other imaging means; 3.Age >= 70 years old; 4.High risk factors such as emphysema, pulmonary fibrosis, pulmonary insufficiency or cardiovascular and cerebrovascular diseases; 5.Intolerance or definite refusal of surgery or chemotherapy.

Exclusion criteria

Exclusion criteria: 1.Severe bleeding tendency, platelet less than 50 × 109 / L and severe coagulation disorder; 2.Unable to cooperate with biopsy, microwave ablation or radiotherapy; 3.ECoG score > 3; 4.Severe systemic infection, high fever, skin infection and ulceration at puncture / irradiation site.

Design outcomes

Primary

Measure	Time frame
Local efficacy;Disease free survival rate;	—

Secondary

Measure	Time frame
Quality of life score;Pulmonary function;complication;	—

Countries

China

Contacts

Public ContactLi Xiaoguang

Beijing Hospital

xglee88@126.com+86 10 85132997

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026