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Clinical study and prognostic factors of minimally invasive interventional therapy for unresectable stage III non-small cell lung cancer in the elderly

Clinical study and prognostic factors of minimally invasive interventional therapy for unresectable stage III non-small cell lung cancer in the elderly

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045132
Enrollment
Unknown
Registered
2021-04-07
Start date
2021-04-02
Completion date
Unknown
Last updated
2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Research Group:Comprehensive minimally invasive interventional therapy
Control Group :Concurrent / sequential chemoradiotherapy

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
70 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.The patient voluntarily participated and signed the informed consent; 2.The patient's age was over 70 years old (subject to the date of signing the informed consent); 3.The diagnosis of NSCLC was confirmed by pathology (histology or cytology) without EGFR mutation, ALK fusion or ros1 fusion; 4.The patients in the study group were assessed by MDT to be unable to undergo surgery or refused surgery; 5.CT scan showed measurable tumor focus; 6.KPS score >= 60; 7.Results: the function of heart, liver, kidney and lung was normal, and there was no major organ dysfunction; 8.Patients who had not received chemoradiotherapy or minimally invasive interventional therapy within 2 months; 9.The expected survival time is more than 3 months.

Exclusion criteria

Exclusion criteria: 1.Patients with coagulation dysfunction can not be treated with minimally invasive interventional therapy; 2.Previous history of malignant tumor in other parts; 3.Patients with previous severe pulmonary dysfunction, pulmonary ventilation disorder and multiple bullae; 4.Severe infection, uncontrollable diabetes, hypertension and other serious diseases exist; 5.Those who are participating in other clinical trials; 6.There were more than 3 lesions in both lungs.

Design outcomes

Primary

MeasureTime frame
Local efficacy;

Secondary

MeasureTime frame
Progression free survival;Quality of life score;Side effects and complications;Tumor markers;

Countries

China

Contacts

Public ContactLi Xiaoguang

Beijing Hospital

xglee88@126.com+86 10 85132997

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026