Efficacy of Vitamin D Supplementation and Physical Activity in Improving Musculoskeletal Health in Individuals with Chronic Kidney Disease

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100045116

Enrollment

Unknown

Registered

2021-04-07

Start date

2013-11-01

Completion date

Unknown

Last updated

2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease

Interventions

Intervention:Oral Vitamin D plus physical activity

Control:Oral Vitamin D

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 20 to 60 years; 2. CKD stage 2-4; 3. Patients with CKD and having creatinine of >=1.7 mg/dL for men and >=1.4 mg/dL for women will be screened; 4. Vitamin D deficient subjects (<=20 nmol/L) (32); 5. Able to provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with any transplant (due to use of immune-suppression); 2. Patients with CKD 5 or ESRD; 3. Patients receiving dialysis; 4. Patients who are under treatment for Vitamin D deficiency; 5. Patients who have some sort of known vitamin D deficiency related bone disease by history; 6. Subjects already maintained on steroids; 7. Patients Who Have Been On (25 Or 1, 25, OH Vitamin D Supplementation for Vitamin D Repletion- I/M in last One Year; 8. Patients with known chronic inflammatory disease, malignancy; 9. Subjects who cannot perform physical activity due to any disability or limiting condition; 10. Patients with known depression; 11. Patients with calcium and phosphorus product of > 70 mg/dl.

Design outcomes

Primary

Measure	Time frame
Musculoskeletal strength;	—

Countries

Pakistan

Contacts

Public ContactDr Aysha Habib

Aga Khan University

aysha.habib@aku.edu+92 21 34861927

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026