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Proprioceptive balance training improving cerebral cortex activity and brain functional connectivity in patients with chronic ankle instability: a randomized controlled study

Proprioceptive balance training improving cerebral cortex activity and brain functional connectivity in patients with chronic ankle instability: a randomized controlled study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045098
Enrollment
Unknown
Registered
2021-04-06
Start date
2021-04-06
Completion date
Unknown
Last updated
2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic ankle instability

Interventions

Proprioceptive balance training group:Proprioceptive balance training

Sponsors

Beijing Sport University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 40 Years

Inclusion criteria

Inclusion criteria: CAI group: 1.Aged from 16 to 40 years old; 2.More than one time of unilateral ankle varus sprain, without improvement after conservative treatment for half a year or more; 3.The first sprain occurred more than one year before the study, and protective weight-bearing, fixation and / or movement restriction were required for more than 24 hours after the first sprain; 4.Self-reported at least one time of recurrent sprain of the injured ankle and / or sensation 3 to 6 months before the study Unstable, and / or feel "soft", and / or feel pain; 5.CAIT score = 11 ; 7.There is no knee or hip injury affecting function at present; 8.Self report aerobic exercise for at least 90 minutes per week. Coper group: 1.Aged from 16 to 40 years old; 2.More than 1 time of unilateral ankle varus sprain; 3.The first sprain occurred more than 1 year before participating in the study, requiring protective weight-bearing, fixation and / or movement restriction for more than 24 hours after the first sprain; 4.No ankle pain, "softening", and / or repeated sprain, and / or "feeling instability" in the past year; 5.CAIT score >= 28 points; 6.IdFAI score <= 10 points 7.There is no knee or hip injury affecting the function at present; 8.Self report aerobic exercise for at least 90 minutes per week. Normal group: 1.No history of ankle injury; 2.Gender, height (± 10 cm), weight (± 15 kg), age (16-40 years old) matched with one participant with ankle instability; 3.Self reported aerobic exercise at least 90 minutes per week; 4.No knee or hip injury affecting function at present.

Exclusion criteria

Exclusion criteria: 1.Acute ankle sprain; 2.Previous knee, leg or ankle fracture or operation history; 3.Traumatic ankle arthritis; 4.Foot and ankle deformity or ankle osteochondral injury; 5.Medial malleolus deltoid ligament or lower tibiofibular ligament complex injury; 6.Lower limb neuromuscular injury; 7.Any known visual defect except myopia, hyperopia and astigmatism; 8.Known vestibular dysfunction or any known somatosensory deficit (except CAI group); 9.Aerobic exercise <= 90 min per week and received other intervention clinical trials within 3 months.

Design outcomes

Primary

MeasureTime frame
Oxyhemoglobin (HbO2) of cerebral cortex;IdFAI socres;

Secondary

MeasureTime frame
CAIT socres;

Countries

China

Contacts

Public ContactNi Guoxin

Beijing Sport University

fjrehab@163.com+86 18810851317

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026