Laparoscopic surgerydisease
Conditions
Interventions
Experimental group:Manual lung extension + PEEP titration
Sponsors
The First Centre of PLA General Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.ASA I-III; 2.The age ranged from 45 to 80 years; 3.18 kg/m^2 <= BMI <= 30 kg/m^2; 4.Patients undergoing laparoscopic surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1.Patients refused to participate in the experiment and did not sign the informed consent; 2.The patient had symptoms of upper respiratory tract infection or pulmonary infection in recent 4 weeks, and chest X-ray showed pneumonia; 3.Diseases that affect the compliance of chest and lung, such as chicken chest, pectus excavatum, chest trauma and operation history, chronic obstructive pulmonary emphysema, pleural effusion and acute respiratory distress syndrome, etc; 4.History of neuromuscular dysfunction; 5.There were serious cardiovascular events, lung, kidney and hematopoietic system diseases, etc; 6.Patients who had received general anesthesia 7 days before randomization; 7.Patients with mental system diseases and cognitive impairment; patients with previous history of psychotropic drugs and narcotic drugs abuse; 8.Other circumstances in which the researcher judged that the patient was not suitable to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best positive end-expiratory pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| End-expiratory pulmonary impedance;Region value of interest; | — |
Countries
China
Contacts
Public ContactZhang Changsheng
The First Medical Center of Chinese PLA General Hospital
Outcome results
None listed