Cervical degenerative disease
Conditions
Interventions
A group:Zero-notch interbody fusion cage VA
B group:Kangsheng cervical interbody fusion cage
C group:Zero-notch interbody fusion cage
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18~65 years; 2.Patients with single-segment cervical spondylopathy diagnosed based on clinical symptoms, signs and imaging findings; 3.After standard conservative treatment, it is ineffective or the symptoms are progressively aggravated, which affects daily life and work, and requires anterior decompression surgery; 4.The surgical segment is located between C3/4~C6/7; 5.Be able to fully comply with this agreement psychologically and physically, and cooperate with the predetermined treatment plan, fill out the form, and cooperate with the follow-up; 6.After the patient signs the informed consent, it means that the patient has known and agreed to carry out the relevant aspects of this research.
Exclusion criteria
Exclusion criteria: 1.A history of cervical spine surgery and bone fusion of adjacent segments; 2.Ossification of the posterior longitudinal ligament or cervical spinal canal stenosis, spinal fracture, severe osteoporosis, or history of bone metabolic disease; 3.Local infection and ulceration of neck skin, systemic inflammatory diseases, rheumatoid arthritis, uncontrolled diabetes, malignant tumors, active hepatitis, etc.; 4.Persons with mental illness or mental disorder; 5.The general condition is poor, and the important organs are suffering from serious diseases and cannot tolerate surgery; 6.Known to suffer from infectious diseases such as AIDS, syphilis, etc.; 7.Have received immunosuppressant therapy daily for more than 1 month in the past 12 months; 8.Allergy to implant materials (PPEK or titanium alloy); 9.Severe obesity, history of drug abuse; 10.Those who have a pregnancy plan during pregnancy or research; 11.Are participating in other studies that may affect the results of this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fusion rate;T1 slope; | — |
Secondary
| Measure | Time frame |
|---|---|
| C2-7 Cobb angle;Sagittal vertical axis;Japanese Orthopaedic Association Evaluation Treatment Score (Cervical Spine);Cervical spine dysfunction index;Visual analog scale;Summary of Health Survey; | — |
Countries
China
Contacts
Public ContactLiu Hao
West China Hospital, Sichuan University
Outcome results
None listed