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Study on postoperative delirium and cognitive dysfunction in elderly patients after hip surgery based on local brain oxygen saturation anesthesia regulation

Study on postoperative delirium and cognitive dysfunction in elderly patients after hip surgery based on local brain oxygen saturation anesthesia regulation

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100045027
Enrollment
Unknown
Registered
2021-04-03
Start date
2021-05-01
Completion date
Unknown
Last updated
2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative neural complications

Interventions

Experimental group:Increase the depth of anesthesia or lower the patient's body temperature to reduce the oxygen consumption of brain tissue, and maintain PaCO2 adjusted to more than 40mmHg
Control group:None

Sponsors

Shandong Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients with age of 60 years or older; 2.Patients who underwent elective hip surgery; 3.Patients with ASA grade I~III.

Exclusion criteria

Exclusion criteria: 1.Patients with nervous system diseases, cognitive dysfunction, consciousness disorder and severe visual and hearing impairment before operation; 2.Patients with severe cardiovascular and cerebrovascular diseases before operation, cardiac function NYHA grade III and above, atrial fibrillation, frequent angina pectoris, heart valve disease, symptomatic arrhythmia, etc; 3.Patients with severe pulmonary diseases, such as long-term family oxygen therapy, moderate or above ventilation function or diffusion dysfunction; 4.Patients with severe liver and kidney dysfunction; 5.Patients with emergency surgery or alcoholism.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative delirium;Incidence of postoperative cognitive dysfunction;Score of postoperative rest and exercise pain;Postoperative recovery quality;The first time to get out of bed;Quality of postoperative sleep;Incidence of gastrointestinal and other complications during hospitalization and within 30 days after;Postoperative hospital stay and 30-day mortality;

Countries

China

Contacts

Public ContactWang Gongming

Shandong University

tagmwang1971@163.com+86 13305418726

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026