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Effects of intraoperative infusion rates of dexmedetomidine on delirium and acute renal injury after off-pump coronary artery bypass grafting in elderly patients: a medical records based retrospective propensity score matching study

Effects of intraoperative infusion rates of dexmedetomidine on delirium and acute renal injury after off-pump coronary artery bypass grafting in elderly patients: a propensity score-matching study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100045023
Enrollment
Unknown
Registered
2021-04-03
Start date
2021-03-25
Completion date
Unknown
Last updated
2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium and acute kidey injury

Interventions

Group A:0.4-0.9µg/kg/h Dexmedetomidine
Group B:0.4-0.9µg/kg/h Dexmedetomidine

Sponsors

The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Off-pump coronary artery bypass grafting (OPCABG) was performed from January to April 2014 at the First Affiliated Hospital of University of Science and Technology of China; 2.Age 60 years or older; 3.Intraoperative infusion rate of Dexmedetomidine: 0.1-0.9µg/kg/h.

Exclusion criteria

Exclusion criteria: 1.Dexmedetomidine was used intraoperatively but not in the defined group or in the postoperative ICU; 2.Pump coronary artery bypass grafting; 3.Pre-operative history of mental illness; 4.Cardiac arrest during operation.

Design outcomes

Primary

MeasureTime frame
Postoperative delirium;Acute kidney injury;—

Countries

China

Contacts

Public ContactFang Jun

The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)

fjjf123@sina.com+86 13170010298

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026